1,3-Dibromo-5,5-dimethylhydantoin (DBH) as a cheap and efficient catalyst for the synthesis of polyhydroquinolines and 12-aryl-8,9,10,12-tetrahydro [a] xanthene-11-ones

Authors

1 Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran.

2 Department of Chemistry, College of Science, University of Mohaghegh Ardabili, Ardabil, Iran.

3 Department of Chemistry, College of Science, University of Guilan, Rasht, zip code 41335, I.R. Iran. Department of Chemistry, College of Science, University of Mohaghegh Ardabili, Ardabil, Iran.

Abstract

1,3-Dibromo-5,5-dimethylhydantoin (DBH), as a cheap and commercially available reagent, is efficiently able to catalyze the synthesis of polyhydroquinoline derivatives and 12-aryl-8,9,10,12-tetrahydro[a] xanthene-11-ones via one-pot multi-component reactions. This novel synthetic method has the advantages of low cost and availability of the catalyst, short reaction times, high to excellent yields, simple and easy work-up and purification of the products compared to the conventional methods reported in the literature.

Keywords


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