Melamine trisulfonic acid (MTSA) as an efficient catalyst for the synthesis of triazolo[1,2-a]indazole-triones and some 2H-indazolo[2,1-b]phthalazine-triones

Authors

1 Faculty of Chemistry, University of Bu-Ali Sina, 65178, Hamedan, Iran.

2 School of Pharmacy, University of Medical Sciences, Hamedan 65178, Iran.

3 Organic Polymer Chemistry Research Laboratory, Department of Chemistry, Isfahan University of Technology, Isfahan, Iran. Nanotechnology and Advanced Materials Institute, Isfahan University of Technology, Isfahan, Iran.

Abstract

Melamine trisulfonic acid (MTSA) as an efficient heterogeneous catalyst has been used for the one-pot preparation of triazolo[1,2-a]indazole-1,3,8-trione and 2H-indazolo[2,1-b]phthalazine-1,6,11-trione derivatives by the three-component condensation reaction of urazoles or phthalhydrazide, dimedone or 1,3-cyclohexanedione, and aldehydes under solvent-free conditions in good to excellent yields and short reaction times.

Keywords


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