Synthesis of 4,4´-(Arylmethylene)bis(1H-pyrazol-5-ols) catalyzed by nanosilica supported perchloric acid in water

Document Type: Articles

Authors

Department of Chemistry, Yazd Branch, Islamic Azad University, P.O. Box 89195-155, Yazd, Iran.

Abstract

Reaction between aromatic aldehydes and 3–methyl-1-phenyl-2-pyrazoline-5-one catalyzed by nano-SiO2/HClO4 in water under reflux provided a simple and efficient route for the synthesis of 4-((5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)(aryl)methyl)-3-methyl-1-phenyl-1H-pyrazol-5-ol derivatives in high yields.

Keywords


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